Biyografi
Professor Dr. Alaattin ŞEN was born in the village of Ahmetler, Eşme district of Uşak in 1966. He received his B.S. degree in Biology from the Middle East Technical University (METU) in 1989, graduating as his class valedictorian. In the same year, he started his academic career as a research assistant and began his graduate education at METU.
He received his Master's degree in Biology in 1991 and Ph.D. in Biochemistry in 1997 from Graduate School of Natural Sciences at METU. His doctoral thesis was awarded as the thesis of the year by METU Mustafa Parlar Foundation. In the same year, he was also awarded by the 'Outstanding Young Scientist Award' of Turkish Academy of Sciences (TUBA). In 1997, he started to work as an Assistant Professor in the Department of Chemistry at Pamukkale University (PAU) and worked as a postdoctoral researcher for nine months at the Oregon State University in the United States under the support of the Postdoctoral Research Fellowship (TUBITAK NATO-B1).
After being Associate Professor in November 1999, he joined the Biology Department at PAU in 2000. He served as a guest lecturer at the Oregon State University in the United States for a year from 2001-2002 and became a Professor in February 2006. Between the years of 2005-2011, he served as an Executive Committee Member of the of the Basic Scientific Research Group of TÜBİTAK. Since January 2017, he has been serving as the Biological Hazards Commission Member of Food, Agriculture and Livestock Ministry, General Directorate of Food Control, and Risk Assessment Department. He has supervised many projects and thesis. He has been involved in numerous national and several international projects as principal investigator. He has published over 50 international scientific articles and 80 reports, in the indexed journals (SCI). He is the editor of the three chapters in the printed books. He is the chief editor of the Turkish Journal of Biology since March 2018 and the editorial board member of two other indexed international journals. He speaks English well. He is married and father of two children.
He has held senior management positions at Pamukkale Universities including the faculty dean. He is currently working in the Department of Molecular Biology & Genetics at the Faculty of Life and Natural Science at Abdullah Gül University, and also holding the Dean position.
Eğitim Bilgileri
1991 - 1997
1991 - 1997Doktora
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyokimya Anabilim Dalı, Türkiye
1989 - 1991
1989 - 1991Yüksek Lisans
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biology, Türkiye
1984 - 1989
1984 - 1989Lisans
Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Biyolojik Bilimler Bölümü, Türkiye
Yaptığı Tezler
1997
1997Doktora
Purification and characterization of cytochrome P4501A1 and cytochrome P450 reductase from feral leaping mullet (Liza saliens) liver
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyokimya Anabilim Dalı
1991
1991Yüksek Lisans
Effects of benzocaine, benzene, and benzo(a)pyrene on gilthead seabream (Sparus aurata; Sparidae) liver microsomal mixed function oxidase system
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji
Araştırma Alanları
Biyokimya
Moleküler Biyoloji ve Genetik
Akademik Unvanlar / Görevler
2019 - Devam Ediyor
2019 - Devam EdiyorProf.Dr.
Abdullah Gül Üniversitesi, Yaşam Ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji Ve Genetik
2006 - Devam Ediyor
2006 - Devam EdiyorProf.Dr.
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2000 - 2006
2000 - 2006Doç.Dr.
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2001 - 2002
2001 - 2002Araştırmacı
Oregon State University, Yaşam v e Tarım Bilimleri, Moleküler ve Ekolojik Toksikoloji
1997 - 2000
1997 - 2000Yrd.Doç.Dr.
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü
1997 - 1998
1997 - 1998Dr.Öğr.Üyesi
Oregon State University, Yaşam Bilimleri
1997 - 1997
1997 - 1997Araştırma Görevlisi Dr.
Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Biyolojik Bilimler Bölümü
1989 - 1997
1989 - 1997Araştırma Görevlisi
Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Biyolojik Bilimler Bölümü
1990 - 1990
1990 - 1990Araştırmacı
The Weizmann Institute of Science
Yönetimsel Görevler
2020 - Devam Ediyor
2020 - Devam EdiyorBAP Koordinatörü
Abdullah Gül Üniversitesi
2019 - Devam Ediyor
2019 - Devam EdiyorDekan
Abdullah Gül Üniversitesi, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji Ve Genetik
2000 - 2019
2000 - 2019Anabilim/Bilim Dalı Başkanı
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2016 - 2016
2016 - 2016Rektör Yardımcısı
Pamukkale Üniversitesi
2016 - 2016
2016 - 2016Dekan
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi
2012 - 2015
2012 - 2015Fakülte Yönetim Kurulu Üyesi
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2000 - 2012
2000 - 2012Fakülte Kurulu Üyesi
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2000 - 2012
2000 - 2012Bölüm Başkanı
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
2003 - 2006
2003 - 2006Enstitü Müdür Yardımcısı
Pamukkale Üniversitesi, Fen Bilimleri Enstitüsü
2002 - 2006
2002 - 2006Enstitü Yönetim Kurulu Üyesi
Pamukkale Üniversitesi, Fen Bilimleri Enstitüsü
1998 - 2000
1998 - 2000Bölüm Başkan Yardımcısı
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü
1997 - 2000
1997 - 2000Anabilim/Bilim Dalı Başkanı
Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü
Akademi Dışı Deneyim
2011 - 2015
2011 - 2015KURUCU YONETICI
Şirket, ŞEN & ARSLAN BİYOTEKNOLOJİ ARGE ve DANIŞMANLIK, ÜRETİM VE YÖNETİM, KURUCU YONETICI
Verdiği Dersler
Yönetilen Tezler
Devam Ediyor
Devam EdiyorDoktora
Organoidleri Kullanarak Multipl Skleroz için Çoklu Hedefleme - İnsan Serebral Organoidlerinde Fingolimod'a Cinsiyet Yanlılığı Tepkisi
Şen A. (Danışman)
N.AKTAŞ(Öğrenci)
Devam Ediyor
Devam EdiyorDoktora
Multiple Skleroz ve Organoidler / Organoid Uygulayarak Bilişsel Bozukluk ve Multipl Skleroz İçin Çok Hedefli İlaçların Araştırılması
Şen A. (Danışman)
B.ACAR(Öğrenci)
2022
2022Yüksek Lisans
Investigation of the importance of CYP2D6 genotype in mesalazine metabolism
Şen A., Semiz G.(Eş Danışman)
M.Beste(Öğrenci)
2021
2021Yüksek Lisans
Yeni kumarin türevlerinin SH-SY5Y hücre hattı üzerinde anti-alzheimer etkilerinin araştırılması
Şen A. (Danışman)
Ş.Irmak(Öğrenci)
2019
2019Yüksek Lisans
Investigation the treatment efficiency of fingolimod derived novel ST-1505 compound in Multiple sclerosis
Şen A. (Danışman)
F.Sandal(Öğrenci)
2019
2019Yüksek Lisans
Hepatit olgusunda (HBX) NF-kB ve AHR etkileşimleri ilişkisinin araştırılması
Şen A. (Danışman)
N.Ölmez(Öğrenci)
2019
2019Yüksek Lisans
Capparis ovata'dan izole edilen, yeni ve doğal bir bileşik olan 1H-indol- 2-hidroksi, 3-karboksilik asit'in anti-kanser özelliklerinin araştırılması
Şen A. (Danışman)
H.Oruç(Öğrenci)
2019
2019Yüksek Lisans
Capparis ovata'dan İzole Edilen Bazı Bileşiklerin İn vitro Anti-inflamatuar Etkilerinin Araştırılması
Şen A. (Danışman)
H.Abilo(Öğrenci)
2018
2018Yüksek Lisans
Determination of leukocytes infiltrating central nervous system in experimental allergic encephalomyelitis (EAE) model
Şen A. (Danışman)
K.Ertosun(Öğrenci)
2017
2017Doktora
Capparis ovata'dan elde edilen MSCov, alt ekstreleri ve saf bileşiklerin multipl skleroz üzerine etkileri-moleküler mekanizmalar
Şen A. (Danışman)
Ö.Özgün(Öğrenci)
2017
2017Doktora
Multipl skleroz (MS) hastalığının tedavisinde kullanılan fingolimod benzeri ilaçların biyoetkinliklerinin incelenmesi
Şen A. (Danışman)
G.Çelik(Öğrenci)
2016
2016Yüksek Lisans
Investigation of the in vitro anti-diabetic effects of 6- {2-[(5-cyano-4,5- dihydropyrazol-1-yl)-2-oxoethylamino] ethylamino} nicotinonitrile dihydrochloride hydrate
Şen A. (Danışman)
B.Ayar(Öğrenci)
2016
2016Yüksek Lisans
Characterization of CYP450-dependent metabolism of 5-amino salicylic acid
Şen A. (Danışman)
E.Kale(Öğrenci)
2015
2015Doktora
The effects of folk medicinal plants Viscum album L. And Epilobium hirsutum L. on protein and mRNA expressions of rat liver bile acid synthesizing CYPs
Şen A. (Eş Danışman), Adalı O.
T.Çulcu(Öğrenci)
2014
2014Yüksek Lisans
Investigating the molecular mechanisms of the effects of dwarf nettle (Urtica urens) on prostate cancer
Şen A. (Danışman)
G.Terzioğlu(Öğrenci)
2013
2013Doktora
Comprehensive Identification of the Molecular Effects of Hairy Willow on Phase I Enzymes
Şen A. (Eş Danışman), Adalı O.
S.KARAKURT(Öğrenci)
2013
2013Yüksek Lisans
The role of interactions of CYP1A1, HBX and NF-kB in the development of hepatocelular carcinoma
Şen A., Tufan N. L.(Eş Danışman)
T.Koç(Öğrenci)
2012
2012Yüksek Lisans
In vivo effect of Epilobium hirsutum L. and Viscum album L. on protein and mRNA expressions of rat liver vitamin D3 metabolizing CYP24A1 and CYP27B1 enzymes
Şen A. (Eş Danışman), Adali O.
M.Sever(Öğrenci)
2012
2012Yüksek Lisans
Comprehensive identification of the effects of ellagic acid on xenobiotic metabolism and its drug-diet interaction potentials using molecular approaches
Şen A. (Danışman)
G.Çelik(Öğrenci)
2012
2012Doktora
Türkiye Kızıl Çamı (Pinus brutia) 'da Çam Sürüngen Güvesi (Thaumetopoea wilkinsoni) Direncindeki Genetik Varyasyonlarda Sitokrom P450 İfade Düzeylerinin Rollerinin Araştırılması
Şen A. (Danışman)
A.SEMİZ(Öğrenci)
2012
2012Yüksek Lisans
Investigating the molecular mechanisms of the effects of Capparis ovata extract in experimental animal model of multiple sclerosis.
Şen A., Arslan Ş.(Eş Danışman)
Ö.Özgün(Öğrenci)
2011
2011Yüksek Lisans
Catalase from a local Bacillus licheniformis species isolated from pamukkale hot springs: Cloning, expression, purification and characterization
Şen A. (Danışman)
M.Özkarslı(Öğrenci)
2010
2010Yüksek Lisans
Genetic polymorphisms of cytochrome P4501-3 (CYP1-3) and phase II enzymes in turkish ulcerative colitis patients
Şen A. (Danışman)
Ö.Büyükgöze(Öğrenci)
2007
2007Yüksek Lisans
Effect of sulfite oxidase deficiency in xenobiotics metabolism
Şen A. (Danışman)
B.Tütüncü(Öğrenci)
2007
2007Yüksek Lisans
Characterization of brain dibenzylfluorescein o-dibenzylase in gilthead seabream (Sparus Aurata L., 1758)
Şen A. (Danışman)
D.Hançer(Öğrenci)
2006
2006Yüksek Lisans
Characterization of aging of drug metabolizing enzymes and assessment of aging in gilthead seabream (sparus aurata) liver microsomes
Şen A. (Danışman)
H.Ardağ(Öğrenci)
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
2025
2025Role of Long Non-Coding RNA X-Inactive-Specific Transcript (XIST) in Neuroinflammation and Myelination: Insights from Cerebral Organoids and Implications for Multiple Sclerosis
Pepe N. A., Acar B., Zararsiz G. E., Guner S. A., Şen A.
Non-Coding RNA , cilt.11, sa.3, ss.1-31, 2025 (SCI-Expanded)
2025
2025Therapeutic Potential of Nitrogen‐Substituted Oleanolic Acid Derivatives in Neuroinflammatory and Cytokine Pathways: Insights From Cell‐Based and Computational Models
Turgut G. Ç., Pepe N. A., Ekiz Y. C., Şenol H., Şen A.
Chemistry & Biodiversity , cilt.0, sa.0, ss.1-31, 2025 (SCI-Expanded)
2024
2024Amelioration potential of synthetic oxime chemical cores against multiple sclerosis and Alzheimer's diseases: Evaluation in aspects of in silico and in vitro experiments
Yilmaz A., Koca M., Ercan S., Acar O. O., Boga M., Sen A., et al.
Journal of Molecular Structure , cilt.1318, 2024 (SCI-Expanded)
2024
2024Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer’s Disease
Akyürek T. U., Orhan I. E., Deniz F. S. Ş., Eren G., Acar B., Sen A.
Pharmaceuticals , cilt.17, sa.11, 2024 (SCI-Expanded)
2023
2023Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cells
Celik-Turgut G., Olmez N., Koc T., Ozgun-Acar O., SEMİZ A., DODURGA Y., et al.
GENE , cilt.853, 2023 (SCI-Expanded)
2023
2023Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors
Şenol H., Çelik Turgut G., Şen A., Sağlamtaş R., Tuncay S., Gülçin I., et al.
MEDICINAL CHEMISTRY RESEARCH , cilt.00, sa.00, ss.1-11, 2023 (SCI-Expanded)
2023
2023Synthesis and Comprehensive in Vivo Activity Profiling of Olean-12-en-28-ol, 3β-Pentacosanoate in Experimental Autoimmune Encephalomyelitis: A Natural Remyelinating and Anti-Inflammatory Agent
ŞENOL H., Ozgun-Acar O., DAĞ A., EKEN A., GÜNER H., Aykut Z. G., et al.
Journal of Natural Products , cilt.86, sa.1, ss.103-118, 2023 (SCI-Expanded)
2022
2022Evaluation of Anti-Alzheimer Activity of Synthetic Coumarins by Combination of in Vitro and in Silico Approaches
Erdoğan Orhan I., Şenol Deniz F. S., Salmas R. E., Irmak S., Acar O. O., Turgut G. C., et al.
CHEMISTRY & BIODIVERSITY , cilt.19, 2022 (SCI-Expanded)
2022
2022Biochemical, pharmacological, and toxicological attributes of caper (Capparis ovata) flowering buds and berries pickles
Ozgun-Acar O., Celik-Turgut G., GÜNER H., Sezer S., ŞEN A.
FOOD SCIENCE & NUTRITION , cilt.10, sa.12, ss.4189-4200, 2022 (SCI-Expanded)
2022
2022Cerium Oxide Nanoparticles Biosynthesized Using Fresh Green Walnut Shell in Microwave Environment and their Anticancer Effect on Breast Cancer Cells
Sulak M., Turgut G. C., ŞEN A.
CHEMISTRY & BIODIVERSITY , cilt.19, sa.8, 2022 (SCI-Expanded)
2022
2022Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes
Şen A.
TURKISH JOURNAL OF MEDICAL SCIENCES , cilt.52, sa.5, ss.1425-1447, 2022 (SCI-Expanded)
2020
2020Suppression of inflammatory cytokines expression with bitter melon (Momordica charantia) in TNBS-instigated ulcerative colitis
SEMİZ A., Acar O. O., ÇETİN SORKUN H., SEMİZ G., ŞEN A.
JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE , cilt.8, sa.3, ss.177-187, 2020 (SCI-Expanded)
2020
2020Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases
ŞEN A.
WORLD JOURNAL OF CLINICAL CASES , cilt.8, sa.10, ss.1767-1792, 2020 (SCI-Expanded)
2020
2020Triterpenoids and steroids isolated from Anatolian Capparis ovata and their activity on the expression of inflammatory cytokines
GAZİOĞLU I., Semen S., Acar O. O., KOLAK U., Sen A., TOPÇU G.
PHARMACEUTICAL BIOLOGY , cilt.58, sa.1, ss.925-931, 2020 (SCI-Expanded)
2019
2019Synthesis and initial evaluation of efficacy of olean-12-en-28-ol, 3 beta-pentacosanoate for the symptomatic treatment of multiple sclerosis
ŞEN A., ŞENOL H., Acar O. O., Kale E., DAĞ A., TOPÇU G.
FEBS OPEN BIO , cilt.9, ss.74, 2019 (SCI-Expanded)
2019
2019Role of cytochrome P450 polymorphisms and functions in development of ulcerative colitis
ŞEN A., Stark H.
WORLD JOURNAL OF GASTROENTEROLOGY , cilt.25, sa.23, ss.2846-2862, 2019 (SCI-Expanded)
2019
2019Natural diterpenoid alysine A isolated from Teucrium alyssifolium exerts antidiabetic effect via enhanced glucose uptake and suppressed glucose absorption
Sen A., Ayar B., Yilmaz A., Acar O. O., Turgut G. C., TOPÇU G.
TURKISH JOURNAL OF CHEMISTRY , cilt.43, sa.5, ss.1350-1372, 2019 (SCI-Expanded)
2019
2019EVALUATION OF IN VIVO EFFECTS OF VISCUM ALBUM L. AND ITS CONSTITUENT O-COUMARIC ACID ON BILE ACID SYNTHESIZING CYPS
Ege T., Ozkan A. M. G., Sen A., ADALI O.
FRESENIUS ENVIRONMENTAL BULLETIN , cilt.28, sa.4, ss.2825-2834, 2019 (SCI-Expanded)
2018
2018Alteration of drug pharmacokinetics with medicinal plant Viscum album L. by rendering major cytochrome P450 activities
Sen A., Celik-Turgut G., Gencler-Ozkan A. M. G., ADALI O.
FEBS OPEN BIO , cilt.8, ss.229, 2018 (SCI-Expanded)
2018
2018Synthesis of novel acridine-sulfonamide hybrid compounds as acetylcholinesterase inhibitor for the treatment of alzheimer's disease
Ulus R., Esirden I., Aday B., Turgut G. C., Sen A., Kaya M.
MEDICINAL CHEMISTRY RESEARCH , cilt.27, sa.2, ss.634-641, 2018 (SCI-Expanded)
2017
2017Synthesis and Functional Investigations of Computer Designed Novel Cladribine-Like Compounds for the Treatment of Multiple Sclerosis
Yavuz S., Cetin A., AKDEMİR A., Doyduk D., Disli A., Celik Turgut G., et al.
ARCHIV DER PHARMAZIE , cilt.350, sa.11, 2017 (SCI-Expanded)
2017
2017In vivo examination of the effects of hydroxycinnamic acid on xenobiotic metabolizing and antioxidant enzymes
Semiz A., Celik-Turgut G., Karakurt S., Akca H., Arslan S., ADALI O., et al.
ARCHIVES OF BIOLOGICAL SCIENCES , cilt.69, sa.1, ss.103-110, 2017 (SCI-Expanded)
2017
2017Computer design, synthesis, and bioactivity analyses of drugs like fingolimod used in the treatment of multiple sclerosis
Turgut G. C., Doyduk D., Yildirir Y., Yavuz S., AKDEMİR A., Disli A., et al.
BIOORGANIC & MEDICINAL CHEMISTRY , cilt.25, sa.2, ss.483-495, 2017 (SCI-Expanded)
2016
2016Modulatory role of GSTM1 null genotype on the frequency of micronuclei in pesticide-exposed agricultural workers
Tumer T. B., Savranoglu S., Atmaca P., Terzioglu G., Sen A., Arslan S.
TOXICOLOGY AND INDUSTRIAL HEALTH , cilt.32, sa.12, ss.1942-1951, 2016 (SCI-Expanded)
2016
2016The isolation of tetrangomycin from terrestrial Streptomyces sp CAH29: evaluation of antioxidant, anticancer, and anti-MRSA activity
Ozakin S., Davis R. W., Umile T. P., Pirinccioglu N., Kizil M., Celik G., et al.
MEDICINAL CHEMISTRY RESEARCH , cilt.25, sa.12, ss.2872-2881, 2016 (SCI-Expanded)
2016
2016Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
Ozgun-Acar O., Celik-Turgut G., GAZİOĞLU I., KOLAK U., Ozbal S., Ergur B. U., et al.
JOURNAL OF NEUROIMMUNOLOGY , cilt.298, ss.106-116, 2016 (SCI-Expanded)
2016
2016Inhibitory action of Epilobium hirsutum extract and its constituent ellagic acid on drug-metabolizing enzymes
Celik G., Semiz A., Karakurt S., Gencler-Ozkan A. M., Arslan S., ADALI O., et al.
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS , cilt.41, sa.2, ss.109-116, 2016 (SCI-Expanded)
2016
2016Association between herbivore stress and glutathione S-transferase expression in Pinus brutia Ten.
Semiz A., Celik-Turgut G., Semiz G., Ozgun O., Sen A.
CELLULAR AND MOLECULAR BIOLOGY , cilt.62, sa.3, ss.89-94, 2016 (SCI-Expanded)
2016
2016Contribution of ellagic acid on the antioxidant potential of medicinal plant Epilobium hirsutum
Karakurt S., Semiz A., Celik G., Gencler-Ozkan A. M., Sen A., ADALI O.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL , cilt.68, sa.1, ss.173-183, 2016 (SCI-Expanded)
2015
2015Investigation of Chironomidae (Diptera) relationships using mitochondrial COI gene
Sari A., Duran M., Sen A., Bardakci F.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY , cilt.59, ss.229-238, 2015 (SCI-Expanded)
2015
2015Cloning and expression of a CYP720B orthologue involved in the biosynthesis of diterpene resin acids in Pinus brutia
Semiz A., Sen A.
MOLECULAR BIOLOGY REPORTS , cilt.42, sa.3, ss.737-744, 2015 (SCI-Expanded)
2015
2015Modulatory actions of o-coumaric acid on carcinogen-activating cytochrome P450 isozymes and the potential for drug interactions in human hepatocarcinoma cells
Sen A., Terzioglu G., Atmaca P., Celik G., Ozgun O., Arslan S.
PHARMACEUTICAL BIOLOGY , cilt.53, sa.9, ss.1391-1398, 2015 (SCI-Expanded)
2013
2013Anticarcinogenic Effect and Carcinogenic Potential of the Dietary Phenolic Acid: o-Coumaric Acid
Sen A., Atmaca P., Terzioglu G., Arslan S.
NATURAL PRODUCT COMMUNICATIONS , cilt.8, sa.9, ss.1269-1274, 2013 (SCI-Expanded)
2013
2013Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
Karakurt S., Semiz A., Celik G., Gencler-Ozkan A. M., Sen A., ADALI O.
PHARMACEUTICAL BIOLOGY , cilt.51, sa.5, ss.650-658, 2013 (SCI-Expanded)
2013
2013Association of the CYP1A1*2A, GSTT1 null, GSTM1 null, mEPHX*3, and XRCC1-399 genetic polymorphisms with ulcerative colitis
Buyukgoze O., Osmanoglu N., Arslan S., Sen A.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE , cilt.28, sa.4, ss.593-595, 2013 (SCI-Expanded)
2013
2013Investigation of aromotase inhibition by several dietary vegetables in human non-small cell lung cancer cell lines
Celik G., Akca H., Sen A.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.38, sa.2, ss.207-217, 2013 (SCI-Expanded)
2013
2013A Comparative Study for the Evaluation of Two Doses of Ellagic Acid on Hepatic Drug Metabolizing and Antioxidant Enzymes in the Rat
Celik G., Semiz A., Karakurt S., Arslan S., ADALI O., Sen A.
BIOMED RESEARCH INTERNATIONAL , cilt.2013, 2013 (SCI-Expanded)
2012
2012Assessment of the Sediment Toxicity in Bulgarian and Turkish Rivers Using the Biomarkers in Chironomus riparius Mg. (Diptera: Chironomidae)
Duran M., Michailova P., Sari A., Ilkova J., Sen A., Karadurmus E.
ACTA ZOOLOGICA BULGARICA , ss.167-173, 2012 (SCI-Expanded)
2012
2012Alteration of drug metabolizing enzymes in sulphite oxidase deficiency
Tutuncu B., Kucukatay V., Arslan S., Sahin B., Semiz A., Sen A.
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION , cilt.51, sa.1, ss.50-54, 2012 (SCI-Expanded)
2012
2012Diverse action of acrylamide on cytochrome P450 and glutathione S-transferase isozyme activities, mRNA levels and protein levels in human hepatocarcinoma cells
Sen A., Ozgun O., Arinc E., Arslan S.
CELL BIOLOGY AND TOXICOLOGY , cilt.28, sa.3, ss.175-186, 2012 (SCI-Expanded)
2012
2012Structural and functional alterations in salivary gland chromosomes and enzyme activity of Chironomus riparius Mg. (Diptera, Chironomidae) from anthropogenically polluted sites in Bulgaria and Turkey
Michailova P., Ilkova J., Duran M., Karadurmus E., Berber R., Sen A.
CARYOLOGIA , cilt.65, sa.2, ss.157-169, 2012 (SCI-Expanded)
2011
2011Polycyclic Aromatic Hydrocarbons in Water from the Menderes River, Turkey
Ardag H., Ozel M. Z., Sen A.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY , cilt.86, sa.2, ss.221-225, 2011 (SCI-Expanded)
2011
2011EROD and metallothionein in Limnodrilus profundicola (Oligochaeta: Tubificidae) as an indicator of pollution exposure in the Curuksu stream of Menderes river, Denizli-Turkey
Ozdemir A., Duran M., Akyildiz G. K., Sen A.
DESALINATION AND WATER TREATMENT , cilt.26, ss.98-103, 2011 (SCI-Expanded)
2011
2011Potential Use of the Oligochaete Limnodrilus profundicola V., as a Bioindicator of Contaminant Exposure
Ozdemir A., Duran M., Sen A.
ENVIRONMENTAL TOXICOLOGY , cilt.26, sa.1, ss.37-44, 2011 (SCI-Expanded)
2011
2011EFFECTS OF CYCLAMEN TROCHOPTERANTHUM ON HEPATIC DRUG-METABOLIZING ENZYMES
Arslan S., Ozgun O., Celik G., Semiz A., Dusen O., Mammadov R., et al.
ARCHIVES OF BIOLOGICAL SCIENCES , cilt.63, sa.3, ss.545-555, 2011 (SCI-Expanded)
2010
2010Determination of 7-ethoxyresorufin-o-deethylase (EROD) induction in leaping mullet (Liza saliens) from the highly contaminated Aliaga Bay, Turkey
Sen A., Ulutas O. K., Tutuncu B., Ertas N., Cok I.
ENVIRONMENTAL MONITORING AND ASSESSMENT , cilt.165, ss.87-96, 2010 (SCI-Expanded)
2010
2010Characterization of drug metabolizing enzymes and assessment of aging in the gilthead seabream (Sparus aurata) liver
Akdogan H. A., Sen A.
VETERINARNI MEDICINA , cilt.55, sa.9, ss.463-471, 2010 (SCI-Expanded)
2009
2009Drug Interaction Potential of the Seed Extract of Urtica urens L. (Dwarf Nettle)
Agus H. H., Tekin P., Bayav M., Semiz A., Sen A.
PHYTOTHERAPY RESEARCH , cilt.23, sa.12, ss.1763-1770, 2009 (SCI-Expanded)
2009
2009ENVIRONMENTAL AND DIETARY FACTORS ON CANCER WITH REGARD TO CYP450
Sen A.
IUBMB LIFE , cilt.61, sa.3, ss.295-296, 2009 (SCI-Expanded)
2008
2008In vivo effects of Urtica urens (dwarf nettle) on the expression of CYP1A in control and 3-methylcholanthrene-exposed rats
Ozkarsli M., Sevim H., Sen A.
XENOBIOTICA , cilt.38, sa.1, ss.48-61, 2008 (SCI-Expanded)
2007
2007Effects of metals and detergents on biotransformation and detoxification enzymes of leaping mullet (Liza saliens)
Sen A., Semiz A.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY , cilt.68, sa.3, ss.405-411, 2007 (SCI-Expanded)
2007
2007Determination of heavy metals and EROD induction in mullet from highly contaminated Aliaga Bay, Izmir, Turkey
Ulutas O. K., Ertas N., Sen A., Tutuncu B., Cok I.
TOXICOLOGY LETTERS , cilt.172, 2007 (SCI-Expanded)
2007
2007Antioxidant and chemoprotective properties of Momordica charantia L. (bitter melon) fruit extract
Semiz A., Sen A.
AFRICAN JOURNAL OF BIOTECHNOLOGY , cilt.6, sa.3, ss.273-277, 2007 (SCI-Expanded)
2004
2004Biochemical characterization and distribution of glutathione S-transferases in leaping mullet (Liza saliens)
Sen A., Kirikbakan A.
Biokhimiya , cilt.69, sa.9, ss.1223-1232, 2004 (SCI-Expanded)
2004
2004cDNA-directed expression of a functional zebrafish CYP1A in yeast
Chung W., Sen A., Wang-Buhler J., Yang Y., Lopez N., Merrill G., et al.
AQUATIC TOXICOLOGY , cilt.70, sa.2, ss.111-121, 2004 (SCI-Expanded)
2004
2004Biochemical characterization and distribution of glutathione S-transferases in leaping mullet (Liza saliens)
Sen A., Kirikbakan A.
BIOCHEMISTRY-MOSCOW , cilt.69, sa.9, ss.993-1000, 2004 (SCI-Expanded)
2002
2002Liquid-liquid extraction of transition metal cations by nine new azo derivatives calix[n]arene
Akdogan A., Deniz M., Cebecioglu S., Sen A., Deligoz H.
SEPARATION SCIENCE AND TECHNOLOGY , cilt.37, sa.4, ss.973-980, 2002 (SCI-Expanded)
2001
2001Immunohistochemical localization and differential expression of cytochrome P450 3A27 in the gastrointestinal tract of rainbow trout
Lee S., Hedstrom O., Fischer K., Wang-Buhler J., Sen A., Cok I., et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY , cilt.177, sa.2, ss.94-102, 2001 (SCI-Expanded)
2001
2001Cloning, sequencing, and characterization of CYP1A1 cDNA from leaping mullet (Liza saliens) liver and implications for the potential functions of its conserved amino acids
Sen A., Hu C., Urbach E., Wang-Buhler J., Yang Y., Arinc E., et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , cilt.15, sa.5, ss.243-255, 2001 (SCI-Expanded)
2000
2000Further immunochemical and biocatalytic characterization of CYP1A1 from feral leaping mullet liver (Liza saliens) microsomes
Sen A., Arinc E.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY , cilt.126, sa.3, ss.235-244, 2000 (SCI-Expanded)
2000
2000Cytochrome P4501A and associated mixed-function oxidase induction in fish as a biomarker for toxic carcinogenic pollutants in the aquatic environment
Arinc E., Sen A., Bozcaarmutlu A.
PURE AND APPLIED CHEMISTRY , cilt.72, sa.6, ss.985-994, 2000 (SCI-Expanded)
1999
1999Hepatic cytochrome P4501A and 7-ethoxyrcsorufin O-deethylase induction in mullet and common sole as an indicator of toxic organic pollution in Izmir Bay, Turkey
Arinc E., Sen A.
MARINE ENVIRONMENTAL RESEARCH , cilt.48, sa.2, ss.147-160, 1999 (SCI-Expanded)
1998
1998Preparation of highly purified cytochrome P4501A1 from leaping mullet (Liza saliens) liver microsomes and its biocatalytic, molecular and immunochemical properties
Sen A., Arinc E.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY , cilt.121, ss.249-265, 1998 (SCI-Expanded)
1998
1998Purification and Characterization of Cytochrome P450 Reductase from Liver Microsomes of Feral Leaping Mullet (Liza saliens)
Sen A., Arinc E.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY , cilt.12, sa.2, ss.103-113, 1998 (SCI-Expanded)
1997
1997Separation of three P450 isozymes from liver microsomes of gilthead seabream treated with β-NF and partial purification of cytochrome P4501A1
Şen A., Arinç E.
Biochemistry and Molecular Biology International , cilt.41, sa.1, ss.131-141, 1997 (SCI-Expanded)
1997
1997Separation of three P450 isozymes from liver microsomes of gilthead seabream treated with D-NF and partial purification of cytochrome P4501A1
Sen A., Arinc E.
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL , cilt.41, sa.1, ss.131-141, 1997 (SCI-Expanded)
1995
1995Tissue- and species-dependent expression of sheep lung microsomal cytochrome p4502B(LgM2)
Arinc E., Hanukoglu I., Sen A., ADALI O.
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL , cilt.37, sa.6, ss.1121-1126, 1995 (SCI-Expanded)
1994
1994EFFECTS OF IN-VIVO BENZO(A)PYRENE TREATMENT ON LIVER MICROSOMAL MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS-AURATA)
ARINC E., SEN A.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY , cilt.107, sa.3, ss.405-414, 1994 (SCI-Expanded)
1994
1994IN-VIVO EFFECTS OF THE ANESTHETIC, BENZOCAINE, ON LIVER MICROSOMAL CYTOCHROME-P450 AND MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS-AURATA)
ARINC E., SEN A.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY , cilt.107, sa.3, ss.399-404, 1994 (SCI-Expanded)
1993
1993CHARACTERIZATION OF CYTOCHROME-P450 DEPENDENT MIXED-FUNCTION OXIDASE SYSTEM OF GILTHEAD SEABREAM (SPARUS-AURATA, SPARIDAE) LIVER
ARINC E., SEN A.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY , cilt.104, sa.1, ss.133-139, 1993 (SCI-Expanded)
1993
1993EFFECTS OF INVIVO BENZENE TREATMENT ON CYTOCHROME-P450 AND MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS-AURATA) LIVER-MICROSOMES
ARINC E., SEN A.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY , cilt.104, sa.1, ss.61-65, 1993 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
2025
2025Possible Drug-Drug Interactions between Mesalamine and Tricyclic Antidepressants Through CYP2D6 Metabolism - In silico and in vitro Analyses
Ozen M. B., Gazioglu I., Ozgun Acar O., Guner H., Semiz G., Sen A.
Drug Research , 2025 (ESCI)
2021
2021Apatinib sensitizes human breast cancer cells against navitoclax and venetoclax despite up-regulated bcl-2 and mcl-1 gene expressions
Kavakcioglu Yardimci B., Ozgun Acar O., SEMİZ A., ŞEN A.
Turk Onkoloji Dergisi , cilt.36, sa.1, ss.8-16, 2021 (ESCI)
2018
2018Effects of folk medicinal plant epilobium hirsutum l. And its ingredient ellagic acid on rat liver bile acid synthesizing cyps in rats
Ege T., Gençler-özkan A., Şen A., ADALI O.
Pharmacologyonline , cilt.3, ss.200-215, 2018 (Scopus)
2017
2017A potential therapeutic role in multiple sclerosis for stigmast-5,22-dien-3 beta-ol myristate isolated from Capparis ovata
Acar O. O., GAZİOĞLU I., KOLAK U., Sen A., TOPÇU G.
EUROBIOTECH JOURNAL , cilt.1, sa.3, ss.241-246, 2017 (ESCI)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2024
2024The Effects of Cinnamic Acid and Autophagy Inhibition on Myelination of Co- cultured Cells
Aktaş Pepe N., Acar B., Şansaçar M., Gencer Akçok E. B., Şen A.
12. International Drug Chemistry Congress, Antalya, Türkiye, 8 - 10 Mart 2024, ss.84, (Özet Bildiri)
2023
2023Yeni hibrit bileşik 4-((1-(3-nitrobenzil)-4,5-dihidro-1H-1,2,3-triazol-4-il)metoksi)benzohidrazidin anti-inflamatuar aktivitelerinin araştırılması
Aktaş Pepe N., Atalay T. N., Acar B., Şenol H., Şen A.
FEBS, Tours, Fransa, 8 - 12 Temmuz 2023, cilt.13, sa.2, ss.103, (Özet Bildiri)
2023
2023Investigating multitargeting effect of fingolimod/ciproxifan butterfly derivatives for multiple sclerosis on brain organoids
Acar B., Stark H., Şen A.
FEBS, Tours, Fransa, 8 - 12 Temmuz 2023, cilt.13, sa.2, ss.193
2021
2021Optimization of myelination on human cerebral organoids for studying multiple sclerosis (MS)
Acar B., Aktaş Pepe N., Şen A.
European Biotechnology Congress 2021, 23 - 25 Eylül 2021, cilt.5, ss.58
2021
2021Opposite effects of even and odd-numbered long chain fatty acids on expression of myelination related genes in human oligodendroglioma cells genes in human oligodendroglioma cells
Aktaş Pepe N., Dilbaz I. S., Metin E., Acar B., Şen A.
European Biotechnology Congress 2021, 23 - 25 Eylül 2021, cilt.5, ss.58
2018
2018Tetrangomycin from Streptomyces stramineus CAH29 and its antimicrobial and cytotoxic activities
Ozakin S., Sen A., Ince E.
European Biotechnology Congress, Athens, Yunanistan, 26 - 28 Nisan 2018, cilt.280
2017
2017Stigmast-5,22-dien-3 beta-ol myristate isolated from Capparis ovata having anti-inflammatory and immunomodulatory actions could be of interest for use in multiple sclerosis
Sen A., Acar O. O., GAZİOĞLU I., KOLAK U., TOPÇU G.
European Biotechnology Congress, Dubrovnik, Hırvatistan, 25 - 27 Mayıs 2017, cilt.256
2016
2016Initial screening the anti-cancer effect of Vitexagnus castus in neuroblastoma cell lines
Bozagac N., Turgut G. C., Semiz G., Semiz A., Sen A.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.255
2016
2016Evaluation of anti-diabetic potential of circiliol and circilineol using CACO2 cell line
Ayar B., Sen A., TOPÇU G., Yilmaz A.
41st Congress of the Federation-of-European-Biochemical-Societies (FEBS) on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.377
2016
2016Beneficial actions of dichloromethane sub-fraction of the COWE extract for multiple sclerosis: a potential therapeutic role
Acar O. O., Sen A., TOPÇU G., GAZİOĞLU I., KOLAK U., Arslan S.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.358
2016
2016A promising novel antidiabetic compound: Alysine-A
Sen A., Ayar B., TOPÇU G., Yilmaz A.
41st Congress of the Federation-of-European-Biochemical-Societies (FEBS) on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.97-98
2016
2016F3-A13 h, novel fingolimod derivative, activates cAMP-dependent signalling pathway in SK-N-SH cell line
Turgut G. C., Sen A., Doyduk D., Yildirir Y.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.268
2016
2016Neuroprotective and immunomodulatory effects of Urtica urens
Arslan S., Terzioglu G., Kabalay B., Tufekci A. R., Sen A., Demirtas I.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.296
2016
2016In vitro investigaton of anti-cancer effect of Pinus nigra Arnold subsp pallasiana (Lamb.) Holmboe essential oil in neuroblastoma cells (SH-SY5Y)
Semiz A., Celik-Turgut G., Semiz G., Kale E., Sen A.
41st FEBS Congress on Molecular and Systems Biology for a Better Life, Kusadasi, Türkiye, 3 - 08 Eylül 2016, cilt.283, ss.257
2015
2015Capparis ovate ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice
Ozgun O., Turgut G. C., GAZİOĞLU I., Kolat U., Ozbal S., Ergur B. U., et al.
31st Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Barcelona, İspanya, 7 - 10 Ekim 2015, cilt.21, ss.671-672
2014
2014Assessing of anti-inflammatory effect of Small nettle' (Urtica urens) increasing polarity extracts
Arslan S., Terzioglu G., Elcil S., Deligoz H., Sen A.
12th International Congress of Neuroimmunology (ISNI), Mainz, Almanya, 9 - 13 Kasım 2014, cilt.275, ss.135
2014
2014Anti-neuroinflammatory effect of butanolic subextract of Capparis ovata water extract used as an alternative and complementary treatment for multiple sclerosis
Sen A., TOPÇU G., Ozgun O., KOLAK U., Hacibekiroglu I., Celik G., et al.
12th International Congress of Neuroimmunology (ISNI), Mainz, Almanya, 9 - 13 Kasım 2014, cilt.275, ss.172-173
2014
2014Capparis ovata water extract (MSCov) for the potential treatment of multiple sclerosis without drug interaction: molecular evidences
Ozgun O., Celik G., Arslan S., Sen A.
FEBS EMBO 2014 Conference, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, cilt.281, ss.104-105
2014
2014Toxicogenomic analysis of Capparis ovata water extract (MSCov)
Celik G., Ozgun O., Arslan S., Sen A.
FEBS EMBO 2014 Conference, Paris, Fransa, 30 Ağustos - 04 Eylül 2014, cilt.281, ss.184
2013
2013Modulation of protein and mRNA expressions of rat liver vitamin D3 metabolizing CYP27B1 by o-coumaric acid
ADALI O., Sever M., Karakurt S., Sen A.
38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey Ve Alderney, 6 - 11 Temmuz 2013, cilt.280, ss.174-175
2013
2013Cloning and expression of CYP720B from Pinus brutia involved in the biosynthesis of diterpene resin acids
Semiz A., Sen A.
European Biotechnology Congress, Bratislava, Slovakya, 16 - 18 Mayıs 2013, cilt.24
2013
2013Antiproliferative and anticarcinogenic effects of an aqueous preparation of Urtica urens in human hepatocarcinoma HepG2 cells
Sen A., Arslan S.
38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey Ve Alderney, 6 - 11 Temmuz 2013, cilt.280, ss.214-215
2012
2012In vivo effect of epilobium hirsutum on xenobiotic metabolising CYP2E1, CYP1A1, glutathione peroxidase and NAD(P)H:quinone oxidoreductase 1 enzymes in rat liver
Karakurt S., Semiz A., Celik G., Gencler-Ozkan A. M., Sen A., ADALI O.
22nd IUBMB Congress/37th FEBS Congress, Sevilla, İspanya, 4 - 09 Eylül 2012, cilt.279, ss.90
2012
2012The effects of folk medicinal plant viscum album l. On protein and mRNA expressions of CYP27A1 in rat liver
Culcu T., Gencler-Ozkan A. M., Sen A., ADALI O.
22nd IUBMB Congress/37th FEBS Congress, Sevilla, İspanya, 4 - 09 Eylül 2012, cilt.279, ss.97
2011
2011Cloning, expression, purification and characterization of Bacillus licheniformis catalase from Pamukkale Hot Springs
Sen A., Ozkarsli M., Dogan N. M., Semiz A., Arslan S.
European Biotechnology Congress, İstanbul, Türkiye, 28 Eylül - 01 Ekim 2011, cilt.22
2011
2011Effects of ellagic acid on CYP2E1, CYP1A1, CYP1A2, NQO1 and GSTMu enzymes in rat
Sen A., Celik G., Semiz A., Karakurt S., ADALI O.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.241
2011
2011Effect of ellagic acid on p53 and PTEN in various cell lines
Gul O. A., Celik G., Akca H., ADALI O., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.209
2011
2011Antioxidant capacity of epilobium hirsutum in rats
Todurga Z. G., ADALI O., Celik G., Karakurt A. S. S., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.235
2011
2011Antioxidant and drug conjugation potential of cyclamen trochopteranthum
Aynaci H. K., Gonen E., Dogan F., Ozkarsli M., Arslan S., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.196
2011
2011In vivo effects of epilobium hirsutum extract on different glutathione transferase isozymes
Semiz A., Celik G., Karakurt S., Arslan S., Gencler-Ozkan A. M., ADALI O., et al.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.233
2011
2011Anti-cancer effect of bee venom in cervical cancer cells
Urhan R., Terzioglu G., Gul O. A., Atmaca P., Ozgun O., Cetin S., et al.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.230
2011
2011Modulations of drug metabolizing enzymes by in vivo treatment of epilobium hirsutum extract in rat
Ozyurt R., Semiz A., Celik G., Karakurt S., Arslan S., Gencler-Ozkan A. M., et al.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.225-226
2011
2011Modulatory effects of cyclamen trochopteranthum on drug and carcinogen metabolism in heLa cells
Arslan S., Ozgun O., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.194-195
2011
2011Differential effects of cyclamen extract on p450 gene expression in human hepatocarcinoma hepg2 cells
Ozgun O., Arslan S., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.225
2011
2011Bee venom induced apoptosis in human hepatocarcinoma HEPG2 cells
Terzioglu G., Gul O. A., Atmaca P., Cetin S., Ozgun O., Arslan S., et al.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.234-235
2011
2011Diverse action of 5-aminosalicyclic acid on cytochrome P450 expression in human cervical cancer cell line
Yasar I., Ozyurt R., Todurga Z. G., Celik G., Arslan S., Sen A.
36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, İtalya, 25 - 30 Haziran 2011, cilt.278, ss.239-240
2010
2010Differential Effects of Cyclamen Extract on P450 Gene Expression
Arslan S., Ozgun O., Sen A.
9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Türkiye, 4 - 08 Eylül 2010, cilt.42, ss.177-178
2010
2010Dietary Aromatase Inhibitors in Human Non-Small Cell Lung Cancer
Sen A., Akca H., Celik G.
9th International Meeting of the International-Society-for-the-Study-of-Xenobiotics(ISSX), İstanbul, Türkiye, 4 - 08 Eylül 2010, cilt.42, ss.171
2009
2009Possible implications of Cyclamen trochopterantum on human therapeutics
Kapdag M., Arslan S., Ozgun O., Oztas M., Ural M., Dusen O., et al.
34th Congress of the Federation-of-European-Biochemical-Societies, Prague, Çek Cumhuriyeti, 4 - 09 Temmuz 2009, cilt.276, ss.315
2009
2009Cyclamen as an ethnomedicine: is it safe?
Ozgun O., Arslan S., Semiz A., Kapdag M., Oztas M., Mammadov R., et al.
34th Congress of the Federation-of-European-Biochemical-Societies, Prague, Çek Cumhuriyeti, 4 - 09 Temmuz 2009, cilt.276, ss.333
2008
2008Genetic polymorphisms of biotransformation enzymes CYP1A1, P4502A6 and microsomal epoxide hydrolase
Ozkarsli M., Buyukgoze O., Sabah S., Osmanoglu N., Sen A.
Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Yunanistan, 28 Haziran - 03 Temmuz 2008, cilt.275, ss.110
2008
2008Genetic polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2D6, and CYP3A4 in the Turkish population
Semiz A., Aynaci H. K., Kus E., Elmas L., Sen A.
Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Yunanistan, 28 Haziran - 03 Temmuz 2008, cilt.275, ss.110
2008
2008Possible use of endpoint fluorometric 7-methoxy-4-trifluoromethyl coumarin o-demethylase assay for assessment of CYP2C activity in rat liver
Aynaci H. K., Sen A.
Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Yunanistan, 28 Haziran - 03 Temmuz 2008, cilt.275, ss.390
2007
2007Protective effects of annual nettle against chemical carcinogens
Semiz A., Ozkarsli M., Sen A.
32nd Congress of the Federation-of-European-Biochemical-Societies (FEBS), Vienna, Avusturya, 7 - 12 Temmuz 2007, cilt.274, ss.178
2007
2007Brain aromatase of gilthead seabream (Sparcus aurata) using dibenzylfluorescein
Hancer D., Sen A.
32nd Congress of the Federation-of-European-Biochemical-Societies (FEBS), Vienna, Avusturya, 7 - 12 Temmuz 2007, cilt.274, ss.275
2007
2007Changes in protein, activity and mRNA levels of hepatic CYP2E and CYP3A in annual nettle treated Wistar rats
Tekin P., Sen A.
32nd Congress of the Federation-of-European-Biochemical-Societies (FEBS), Vienna, Avusturya, 7 - 12 Temmuz 2007, cilt.274, ss.292
2006
2006A potential role of sulfite oxidase deficiency in xenobiotic metabolism
Tutuncu B., Sen A., Kucukatay V., Sahin B.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.240
2006
2006In vivo assessment of Urtica urens supplementation on rat xenobiotic metabolizing enzymes
Sen A., Agus H. H., Bayav M., Sevim H.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.300
2006
2006Changes of drug metabolizing enzymes activities in senescent gilthead seabream (Sparus aurata)
Akdogan H. A., Sen A.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.140
2006
2006Cholinesterases as potential biomarkers in Tubifex sp.
Ozdemir A., Sen A., Duran M.
31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.291
2006
2006In vivo effects of Urtica urens seed extracts on the cytochrome P450-dependent monooxygenases in the liver, lung, and kidney of control and 3-methylcholanthrene-exposed rats
Sen A., Agus H. H., Bayav M., Sevim H.
14th North American Meeting of the International-Society-for-the-Study-of-Xenobiotics, Rio-Grande, Brezilya, 22 - 26 Ekim 2006, cilt.38, ss.55-56
Desteklenen Projeler
2022 - Devam Ediyor
2022 - Devam EdiyorÜç boyutlu 3B hücre kültüründe Metakrilatlanmış jelatin JelMA ve Matrijelin nöral farklılaşmaya ve organoid oluşumuna etkilerinin karşılaştırmalı olarak incelenmesi
Yükseköğretim Kurumları Destekli Proje
ŞEN A. (Yürütücü), ACAR B., DEMİRTAŞ T. T.
2024 - 2027
2024 - 2027
İnsan vasküler beyin organoidleri kullanarak ukmRNA XIST'in MS etiyopatogenezindeki rolünü belirlemeye yönelik bütünleştirici transkriptomik, proteomik ve makine öğrenimi yaklaşımı
TÜBİTAK Projesi
(Proje Özeti)
Şen A., Ayaz Guner Ş. A., Gungor B., Erturk Zararsiz G., Guner H., Yousef M.
2023 - 2024
2023 - 2024Uzun kodlamayan RNA'nın (X-etkin olmayan spesifik transkript) kadınlarda multipl skleroz yatkınlığındaki rolünün serebral organidlerde transkriptomik ve proteomik yaklaşımlarla araştırılma
Türkiye Sağlık Enstitüleri Başkanlığı (TÜSEB) Araştırma Projesi
(Proje Özeti)
Aktas Pepe N., Şen A., Erturk Zararsiz G., Ayaz Guner S.
Bilimsel Dergilerdeki Faaliyetler
2018 - Devam Ediyor
2018 - Devam EdiyorTurkish Journal Of Biology
Baş Editör
2014 - Devam Ediyor
2014 - Devam EdiyorTURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Editör
Bilimsel Kuruluşlardaki Üyelikler / Görevler
2014 - Devam Ediyor
2014 - Devam Ediyor
European Association for Cancer Research
Üye
2014 - Devam Ediyor
2014 - Devam Ediyor
Moleküler Kanser Araştırma Derneği
Üye
2011 - Devam Ediyor
2011 - Devam EdiyorMoleküler Biyoloji Derneği
Üye
2008 - 2011
2008 - 2011The Society of Environmental Toxicology and Chemistry (SETAC)
Üye
2008 - 2010
2008 - 2010Türk Toksikoloji Derneği
Üye
1997 - 2006
1997 - 2006