Investigation of aromotase inhibition by several dietary vegetables in human non-small cell lung cancer cell lines

Celik G., Akca H., Sen A.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.38, sa.2, ss.207-217, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5505/tjb.2013.62634
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.207-217
  • Anahtar Kelimeler: Aromatase, Aromatase Inhibitors, Non-small cell lung cancer, Laurus nobilis, Mentha piperita, Crocus sativus and Allium porrum, EPIDERMAL-GROWTH-FACTOR, ESTROGEN-RECEPTOR-BETA, BREAST-CANCER, HUMAN AROMATASE, EXPRESSION, GENISTEIN, THERAPY, ALPHA, PHYTOESTROGENS, RESVERATROL
  • Abdullah Gül Üniversitesi Adresli: Hayır

Özet

Objective: In this study we have investigated the effect of extracts obtained from well-known vegetable diets consumed commonly in Mediterranean and Aegean regions of Turkey on the expression of aromatase at protein, mRNA and activity levels in human non-small cell lung cancer cells-PC-3 and PC-14 cell lines.