Investigation of aromotase inhibition by several dietary vegetables in human non-small cell lung cancer cell lines

Celik G., Akca H., Sen A.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.38, no.2, pp.207-217, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.5505/tjb.2013.62634
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.207-217
  • Keywords: Aromatase, Aromatase Inhibitors, Non-small cell lung cancer, Laurus nobilis, Mentha piperita, Crocus sativus and Allium porrum, EPIDERMAL-GROWTH-FACTOR, ESTROGEN-RECEPTOR-BETA, BREAST-CANCER, HUMAN AROMATASE, EXPRESSION, GENISTEIN, THERAPY, ALPHA, PHYTOESTROGENS, RESVERATROL
  • Abdullah Gül University Affiliated: No

Abstract

Objective: In this study we have investigated the effect of extracts obtained from well-known vegetable diets consumed commonly in Mediterranean and Aegean regions of Turkey on the expression of aromatase at protein, mRNA and activity levels in human non-small cell lung cancer cells-PC-3 and PC-14 cell lines.