Modulatory actions of o-coumaric acid on carcinogen-activating cytochrome P450 isozymes and the potential for drug interactions in human hepatocarcinoma cells
PHARMACEUTICAL BIOLOGY, cilt.53, sa.9, ss.1391-1398, 2015 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 9
- Basım Tarihi: 2015
- Doi Numarası: 10.3109/13880209.2015.1014919
- Dergi Adı: PHARMACEUTICAL BIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1391-1398
- Anahtar Kelimeler: Carcinogen activation, cytochrome P450 (CYP), HepG2 cells, PHENOLIC-ACIDS, N-NITROSODIMETHYLAMINE, METABOLIZING-ENZYMES, CHLOROGENIC ACIDS, CIGARETTE-SMOKE, PLANT PHENOLICS, MESSENGER-RNA, HEPATOMA-CELL, EXPRESSION, INDUCTION
- Abdullah Gül Üniversitesi Adresli: Hayır
Özet
Context: Although humans are exposed to o-coumaric acid (OCA) in their diet, there is no available literature related to drug interaction and the carcinogen-activating potential of OCA in the HepG2 cell line.