Metrikler
Yayın
22
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2007 - 2013
2007 - 2013Doktora
University of Wisconsin-Madison, Cellular and Molecular Biology, Amerika Birleşik Devletleri
1997 - 2012
1997 - 2012Lisans
Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Biyolojik Bilimler Bölümü, Türkiye
2002 - 2005
2002 - 2005Yüksek Lisans
Orta Doğu Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Biyoteknoloji Anabilim Dalı, Türkiye
Yaptığı Tezler
2013
2013Doktora
Dissecting the role of estrogen receptor palmitoylation in breast cancer cells 
University of Wisconsin-Madison
Araştırma Alanları
Proteomiks
Kanser Moleküler Biyolojisi
Protein Mühendisliği
Akademik Unvanlar / Görevler
2018 - Devam Ediyor
2018 - Devam EdiyorDr.Öğr.Üyesi
Abdullah Gül Üniversitesi, Yaşam Ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji Ve Genetik
2014 - 2016
2014 - 2016Araştırma Görevlisi Dr.
The University of Wisconsin Madison, Cell and Regenerative Biology
2007 - 2013
2007 - 2013Araştırma Görevlisi
The University of Wisconsin Madison, Cellular and Molecular Biology
Verdiği Dersler
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
2022
20221. An integrative-omics analysis of an industrial clavulanic acid-overproducing Streptomyces clavuligerus
KURT KIZILDOĞAN A., Celik G., unsaldi E., ÖZCAN S., AYAZ GÜNER Ş., ÖZCENGİZ G.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY , cilt.106, sa.18, ss.6139-6156, 2022 (SCI-Expanded)
2021
20212. Proteomic fertility markers in ram sperm
HİTİT M., Ozbek M., AYAZ GÜNER Ş., GÜNER H., Oztug M., BODU M., et al.
ANIMAL REPRODUCTION SCIENCE , cilt.235, 2021 (SCI-Expanded)
2021
20213. Proteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells
Acar M. B., AYAZ GÜNER Ş., Gunaydin Z., KARAKÜKCÜ M., Peluso G., Di Bernardo G., et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY , cilt.9, 2021 (SCI-Expanded)
2021
20214. Why Do Muse Stem Cells Present an Enduring Stress Capacity? Hints from a Comparative Proteome Analysis
Acar M. B., Aprile D., AYAZ GÜNER Ş., GÜNER H., TEZ C., Di Bernardo G., et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , cilt.22, sa.4, 2021 (SCI-Expanded)
2020
20205. Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue
Acar M. B., AYAZ GÜNER Ş., Di Bernardo G., GÜNER H., Murat A., Peluso G., et al.
AGING-US , cilt.12, sa.24, ss.24894-24913, 2020 (SCI-Expanded)
2020
20206. A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions
AYAZ GÜNER Ş., Alessio N., Acar M. B., Aprile D., ÖZCAN S., Di Bernardo G., et al.
CELL COMMUNICATION AND SIGNALING , cilt.18, sa.1, 2020 (SCI-Expanded)
2019
20197. A photocleavable surfactant for top-down proteomics
Brown K. A., Chen B., Guardado-Alvarez T. M., Lin Z., Hwang L., Ayaz-Guner Ş., et al.
NATURE METHODS , cilt.16, sa.5, ss.417-423, 2019 (SCI-Expanded)
2018
20188. Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis
Martin-Garrido A., Biesiadecki B. J., Salhi H. E., Shaifta Y., dos Remedios C. G., Ayaz-Guner Ş., et al.
JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.293, sa.22, ss.8588-8599, 2018 (SCI-Expanded)
2016
20169. A Family of Photolabile Nitroveratryl-Based Surfactants That Self-Assemble into Photodegradable Supramolecular Structures
Hwang L., Guardado-Alvarez T. M., Ayaz-Gunner Ş., Ge Y., Jin S.
LANGMUIR , cilt.32, sa.16, ss.3963-3969, 2016 (SCI-Expanded)
2016
201610. Comprehensive Characterization of AMP-Activated Protein Kinase Catalytic Domain by Top-Down Mass Spectrometry
Yu D., Peng Y., Ayaz-Guner Ş., Gregorich Z. R., Ge Y.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY , cilt.27, sa.2, ss.220-232, 2016 (SCI-Expanded)
2016
201611. MASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics
Cai W., Guner H., Gregorich Z. R., Chen A. J., Ayaz-Guner Ş., Peng Y., et al.
MOLECULAR & CELLULAR PROTEOMICS , cilt.15, ss.703-714, 2016 (SCI-Expanded)
2015
201512. Effective Top-Down LC/MS plus Method for Assessing Actin Isoforms as a Potential Cardiac Disease Marker
Chen Y., Ayaz-Guner Ş., Peng Y., Lane N. M., Locher M. R., Kohmoto T., et al.
ANALYTICAL CHEMISTRY , cilt.87, sa.16, ss.8399-8406, 2015 (SCI-Expanded)
2015
201513. Specific Enrichment of Phosphoproteins Using Functionalized Multivalent Nanoparticles
Hwang L., Ayaz-Guner Ş., Gregorich Z. R., Cai W., Valeja S. G., Jin S., et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , cilt.137, sa.7, ss.2432-2435, 2015 (SCI-Expanded)
2014
201414. Top-down mass spectrometry of cardiac myofilament proteins in health and disease
Peng Y., Ayaz-Guner Ş., Yu D., Ge Y.
PROTEOMICS CLINICAL APPLICATIONS , cilt.8, ss.554-568, 2014 (SCI-Expanded)
2013
201315. Systematic Analyses of the Cytotoxic Effects of Compound 11a, a Putative Synthetic Agonist of Photoreceptor-Specific Nuclear Receptor (PNR), in Cancer Cell Lines
Zhao Z., Wang L., Wen Z., Ayaz-guner Ş., Wang Y., Ahlquist P., et al.
PLOS ONE , cilt.8, sa.9, 2013 (SCI-Expanded)
2013
201316. The impact of antibody selection on the detection of cardiac troponin I
Guy M. J., Chen Y., Clinton L., Zhang H., Zhang J., Dong X., et al.
CLINICA CHIMICA ACTA , cilt.420, ss.82-88, 2013 (SCI-Expanded)
2011
201117. Phosphorylation, but Not Alternative Splicing or Proteolytic Degradation, Is Conserved in Human and Mouse Cardiac Troponin T
Zhang J., Zhang H., Ayaz-Guner Ş., Chen Y., Dong X., Xu Q., et al.
BIOCHEMISTRY , cilt.50, sa.27, ss.6081-6092, 2011 (SCI-Expanded)
2009
200918. In Vivo Phosphorylation Site Mapping in Mouse Cardiac Troponin I by High Resolution Top-Down Electron Capture Dissociation Mass Spectrometry: Ser22/23 Are the Only Sites Basally Phosphorylated
Ayaz-Guner Ş., Zhang J., Li L., Walker J. W., Ge Y.
BIOCHEMISTRY , cilt.48, sa.34, ss.8161-8170, 2009 (SCI-Expanded)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2019
20191. Immunoproteomic Analysis of Acinetobacter baumannii Surface and Secreted Proteins
AYAZ GÜNER Ş., ÖZCAN S.
International Congress ofthe Molecular Biology Association of Turkey, İstanbul, Türkiye, 27 - 29 Eylül 2019
2018
20182. Monophosphorylation of cardiac troponin-I at Ser23/24 regulates cardiac myofibrillar Ca2+sensitivity and modulates calpain-induced proteolysis
Kentish J. C., Martin-Garrido A., Biesiadecki B. J., Salhi H. E., Shaifta Y., Dos Remedios C., et al.
5th Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology, Vienna, Avusturya, 20 - 22 Nisan 2018, cilt.114
2017
20173. Kalp Miyofilamentlerinde Top-Down Proteomik Uygulamaları
AYAZ GÜNER Ş.
2. Ulusal Proteomik Kongresi, İstanbul, Türkiye, 24 - 25 Kasım 2017
2017
20174. Estrogen receptor (ERα) palmitoylation is essential for its membrane localization and the intact function of ERα in breast cancer cell.
AYAZ GÜNER Ş., Elaine A., Xu W.
5th International Congress of the Molecular Biology Association of Turkey, 8 - 10 Eylül 2017
Desteklenen Projeler
2020 - 2022
2020 - 2022B Hücreli Akut Lenfoblastik Lösemi (B-ALL) Yüzey Proteomunun İncelenerek Yeni Kimerik Antijen Reseptörü (CAR) Hedeflerinin Belirlenmesi
TÜBİTAK Projesi
Ayaz Güner Ş., Özcan S.(Yürütücü)
Bilimsel Dergilerdeki Faaliyetler
2019 - Devam Ediyor
2019 - Devam Ediyor