A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions

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AYAZ GÜNER Ş., Alessio N., Acar M. B., Aprile D., ÖZCAN S., Di Bernardo G., ...More

CELL COMMUNICATION AND SIGNALING, vol.18, no.1, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1186/s12964-020-00614-w
  • Journal Name: CELL COMMUNICATION AND SIGNALING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE, Directory of Open Access Journals
  • Abdullah Gül University Affiliated: Yes

Abstract

Background: The term mesenchymal stromal cells (MSCs) designates an assorted cell population comprised of stem cells, progenitor cells, fibroblasts, and stromal cells. MSCs contribute to the homeostatic maintenance of many organs through paracrine and long-distance signaling. Tissue environment, in both physiological and pathological conditions, may affect the intercellular communication of MSCs.