A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions


AYAZ GÜNER Ş. , Alessio N., Acar M. B. , Aprile D., ÖZCAN S., Di Bernardo G., ...Daha Fazla

CELL COMMUNICATION AND SIGNALING, cilt.18, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1186/s12964-020-00614-w
  • Dergi Adı: CELL COMMUNICATION AND SIGNALING

Özet

Background: The term mesenchymal stromal cells (MSCs) designates an assorted cell population comprised of stem cells, progenitor cells, fibroblasts, and stromal cells. MSCs contribute to the homeostatic maintenance of many organs through paracrine and long-distance signaling. Tissue environment, in both physiological and pathological conditions, may affect the intercellular communication of MSCs.