The impact of antibody selection on the detection of cardiac troponin I

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Guy M. J., Chen Y., Clinton L., Zhang H., Zhang J., Dong X., ...Daha Fazla

CLINICA CHIMICA ACTA, cilt.420, ss.82-88, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 420
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.cca.2012.10.034
  • Dergi Adı: CLINICA CHIMICA ACTA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.82-88
  • Abdullah Gül Üniversitesi Adresli: Hayır

Özet

Background: Cardiac troponin I (cTnI) is the current standard biomarker for diagnosing acute myocardial infarction and for risk-stratification of acute coronary syndromes in patients. However, it remains unclear how the epitope specificity of antibodies in immunoassays influences the detection of various modified forms of cTnI.