The impact of antibody selection on the detection of cardiac troponin I


Guy M. J. , Chen Y., Clinton L., Zhang H., Zhang J., Dong X., et al.

CLINICA CHIMICA ACTA, cilt.420, ss.82-88, 2013 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 420
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.cca.2012.10.034
  • Dergi Adı: CLINICA CHIMICA ACTA
  • Sayfa Sayısı: ss.82-88

Özet

Background: Cardiac troponin I (cTnI) is the current standard biomarker for diagnosing acute myocardial infarction and for risk-stratification of acute coronary syndromes in patients. However, it remains unclear how the epitope specificity of antibodies in immunoassays influences the detection of various modified forms of cTnI.