Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue

Acar M. B., AYAZ GÜNER Ş., Di Bernardo G., GÜNER H., Murat A., Peluso G., ...More

AGING-US, vol.12, no.24, pp.24894-24913, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 24
  • Publication Date: 2020
  • Doi Number: 10.18632/aging.202423
  • Journal Name: AGING-US
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.24894-24913
  • Keywords: mesenchymal stromal cells, visceral adipose tissue, senescence, MOUSE MODEL, X-RECEPTOR, SENESCENCE, DIFFERENTIATION, INFLAMMATION, METABOLISM, MECHANISMS, NUMBER
  • Abdullah Gül University Affiliated: Yes

Abstract

The mesenchymal stromal cells (MSCs) residing within the stromal component of visceral adipose tissue appear to be greatly affected by obesity, with impairment of their functions and presence of senescence.