Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue

Acar M. B., AYAZ GÜNER Ş., Di Bernardo G., GÜNER H., Murat A., Peluso G., ...Daha Fazla

AGING-US, cilt.12, sa.24, ss.24894-24913, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 24
  • Basım Tarihi: 2020
  • Doi Numarası: 10.18632/aging.202423
  • Dergi Adı: AGING-US
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.24894-24913
  • Anahtar Kelimeler: mesenchymal stromal cells, visceral adipose tissue, senescence, MOUSE MODEL, X-RECEPTOR, SENESCENCE, DIFFERENTIATION, INFLAMMATION, METABOLISM, MECHANISMS, NUMBER
  • Abdullah Gül Üniversitesi Adresli: Evet

Özet

The mesenchymal stromal cells (MSCs) residing within the stromal component of visceral adipose tissue appear to be greatly affected by obesity, with impairment of their functions and presence of senescence.