Assoc. Prof. EMEL BAŞAK GENCER AKÇOK

Publication Network

Journal articles indexed in SCI, SSCI, and AHCI 13

1. Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells

Subay L. B., Gencer Akçok E. B., Akçok İ.

Molecular Biology Reports , vol.52, no.1, 2025 (SCI-Expanded)

2. Efficacy of combinatorial inhibition of Hedgehog and autophagy pathways on the survival of AML cell lines

Şansaçar M., Pepe N. A., Gencer Akçok E. B., El Khatib M.

Biochemical and Biophysical Research Communications , vol.775, 2025 (SCI-Expanded)

3. Discovery of New Candidates Targeting the SH2 Domains of Spleen Tyrosine Kinase (Syk) Through In Silico Studies

Şansaçar M., Sarı C., Yücel M. S., Gencer Akçok E. B., Akçok İ.

ChemistrySelect , vol.10, no.22, 2025 (SCI-Expanded)

4. Tomatidine, a Steroidal Alkaloid, Synergizes with Cisplatin to Inhibit Cell Viability and Induce Cell Death Selectively on FLT3-ITD+ Acute Myeloid Leukemia Cells

Ayvaz H. B., Yenigül M., Gencer Akçok E. B.

Cell Biochemistry and Biophysics , vol.82, no.3, pp.2889-2900, 2024 (SCI-Expanded) Sustainable Development

5. Inhibition of PI3K-AKT-mTOR pathway and modulation of histone deacetylase enzymes reduce the growth of acute myeloid leukemia cells

Şansaçar M., Sağır H., GENCER AKÇOK E. B.

Medical Oncology , vol.41, no.1, 2024 (SCI-Expanded)

6. Histone Deacetylase Inhibition and Autophagy Modulation Induces a Synergistic Antiproliferative Effect and Cell Death in Cholangiocarcinoma Cells

Yenigül M., GENCER AKÇOK E. B.

ACS Omega , vol.8, no.24, pp.21755-21768, 2023 (SCI-Expanded)

7. Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells

Yenigul M., AKÇOK İ., GENCER AKÇOK E. B.

MOLECULAR BIOLOGY REPORTS , vol.49, no.8, pp.7521-7530, 2022 (SCI-Expanded) Sustainable Development

8. Investigation of the Antitumor Effect of Targeting PI3K-AKT-mTOR Pathway and Histone Deacetylase Enzymes on Acute Myeloid Leukemia Cells

ŞANSAÇAR M., Sagir H., GENCER AKÇOK E. B.

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA , vol.21, 2021 (SCI-Expanded)

9. Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains

Sha F., Gencer E. B., Georgeon S., Koide A., Yasui N., Koide S., et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , vol.110, no.37, pp.14924-14929, 2013 (SCI-Expanded)

10. Mechanisms of resistance to BCR-ABL and other kinase inhibitors

Lamontanara A. J., Gencer E. B., Kuzyk O., Hantschel O.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS , vol.1834, no.7, pp.1449-1459, 2013 (SCI-Expanded)

11. Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance

Camgoz A., Gencer E. B., Ural A. U., Baran Y.

LEUKEMIA & LYMPHOMA , vol.54, no.6, pp.1279-1287, 2013 (SCI-Expanded)

12. A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes

Gencer E. B., URAL A. U., AVCU F., Baran Y.

ANNALS OF HEMATOLOGY , vol.90, no.11, pp.1265-1275, 2011 (SCI-Expanded)

13. Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloidleukemia cells

Camgoz A., Gencer E. B., Ural A. U., AVCU F., Baran Y.

LEUKEMIA & LYMPHOMA , vol.52, no.8, pp.1574-1584, 2011 (SCI-Expanded)

Articles Published in Other Journals 5

1. The Anti-leukemic Effect of the Inhibition of Spleen Tyrosine Kinase and Histone Deacetylase Enzyme Inhibition on the FLT3-ITD(+) Acute Myeloid Leukemia Cells

ŞANSAÇAR M., AKCOK E. B. G.

Erciyes Üniversitesi Fen Bilimleri Enstitüsü Dergisi , vol.41, no.2, pp.708-721, 2025 (Peer-Reviewed Journal)

2. Targeting HDAC enzymes by SAHA enhances the cytotoxic effects of cisplatin on acute myeloid leukemia cells

Şansaçar M., Pekin Ö., Gencer Akçok E. B.

Journal of Experimental and Clinical Medicine (Turkey) , vol.41, no.3, pp.524-529, 2024 (Scopus)

3. Measurement of Autophagic Activity in Cancer Cells with Flow Cytometric Analysis Using Cyto-ID Staining.

Şansaçar M., Gencer Akçok E. B.

Methods in molecular biology (Clifton, N.J.) , 2024 (Scopus)

4. Cytotoxic and Cytostatic Effects of Targeting mTOR and Hedgehog Pathways in Acute Myeloid Leukemia

Cicek E., Kucuktas F. M., YENİGÜL M., AKCOK E. B. G.

EXPERIMED , vol.12, no.3, pp.202-208, 2022 (Scopus) Sustainable Development

5. The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells

YENİGÜL M., GENCER AKCOK E. B.

Cumhuriyet Science Journal , vol.42, no.4, pp.775-780, 2021 (Peer-Reviewed Journal) Sustainable Development

Papers Presented at Peer-Reviewed Scientific Conferences 3

1. Targeting the C-SH2 domain of the Syk kinase by virtual drug screening to identify potential anticancer candidates

Şansaçar M., Akçok İ., Güner H., Gencer Akçok E. B.

9 TH INTERNATIONAL BAU DRUG DESIGN CONGRESS, İstanbul, Turkey, 29 November - 02 December 2023, pp.109, (Summary Text) Sustainable Development

2. Rapamycin and Niacin Combination Exerts Anti-Cancer Effect Through Activation of Autophagy on Acute Myeloid Leukemia Cells

Subay L. B., Gencer Akçok E. B., Akçok İ.

12th International Drug chemistry Congress, Antalya, Turkey, 7 - 10 March 2024, pp.127, (Summary Text) Sustainable Development

3. The Effects of Cinnamic Acid and Autophagy Inhibition on Myelination of Co- cultured Cells

Aktaş Pepe N., Acar B., Şansaçar M., Gencer Akçok E. B., Şen A.

12. International Drug Chemistry Congress, Antalya, Turkey, 8 - 10 March 2024, pp.84, (Summary Text)

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