One-pot vinylogous aldol addition of beta,gamma-unsaturated esters under mild conditions

Akcok İ. , Cagir A.

NEW JOURNAL OF CHEMISTRY, vol.39, no.7, pp.5121-5123, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1039/c5nj00961h
  • Title of Journal : NEW JOURNAL OF CHEMISTRY
  • Page Numbers: pp.5121-5123


We described a one-pot vinylogous aldol addition of methyl 3-butenoate to aromatic aldehydes in the presence of silver salts and the TMSCl-TBAF mixture. The reaction can be done simply by sequentially mixing reagents in situ, and it does not require any catalyst or dienolate ether preparations prior to the reaction.