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CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, vol.90, no.3, pp.233-252, 2014 (SCI-Expanded)
Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There are several histological variants such as papillary and follicular thyroid carcinoma. Many patients with well-differentiated subtypes of DTC are cured by surgery alone or with radioiodine, while poorly differentiated types usually have a worse prognosis. The aggressiveness of thyroid tumors is closely linked to specific gene alterations.