An update on molecular biology of thyroid cancers

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ÖMÜR Ö., Baran Y.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, cilt.90, sa.3, ss.233-252, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 90 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.critrevonc.2013.12.007
  • Dergi Adı: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.233-252
  • Abdullah Gül Üniversitesi Adresli: Hayır

Özet

Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There are several histological variants such as papillary and follicular thyroid carcinoma. Many patients with well-differentiated subtypes of DTC are cured by surgery alone or with radioiodine, while poorly differentiated types usually have a worse prognosis. The aggressiveness of thyroid tumors is closely linked to specific gene alterations.