An update on molecular biology of thyroid cancers

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ÖMÜR Ö., Baran Y.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, vol.90, no.3, pp.233-252, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 90 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1016/j.critrevonc.2013.12.007
  • Journal Name: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.233-252
  • Abdullah Gül University Affiliated: No

Abstract

Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There are several histological variants such as papillary and follicular thyroid carcinoma. Many patients with well-differentiated subtypes of DTC are cured by surgery alone or with radioiodine, while poorly differentiated types usually have a worse prognosis. The aggressiveness of thyroid tumors is closely linked to specific gene alterations.