Image-processing based signal readout method for MRD biochip MRD BiyoçIP Için Görüntü Işleme Temelli Sinyal Elde Etme Metodu


27th Signal Processing and Communications Applications Conference, SIU 2019, Sivas, Turkey, 24 - 26 April 2019 identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • Doi Number: 10.1109/siu.2019.8806457
  • City: Sivas
  • Country: Turkey
  • Keywords: Bright-field microscope, Cell detection, Imageprocessing, Immunomagnetic beads, Micro tiles, MRD biochip
  • Abdullah Gül University Affiliated: Yes


© 2019 IEEE.The response of the cancer patients to chemotherapy treatment varies from person to person. For some patients cancer cells are resistant to treatment and these cells can relapse again which is known as minimal residual disease. A microfluidic-based biochip capable of monitoring minimal residual disease is under development by our research group. The role of the biochip is to capture the target cells, which were separated by immunomagnetic beads on micro square tiles. Then biochips are imaged using a bright field optical microscope and it is planned to perform image-processing methods to detect the target cells, immunomagnetic beads and micro tiles. In this work the current progress of image processing methods for differentiating the immunomagnetic beads and micro tiles is presented.