Antibacterial type-II InP/ZnO quantum dots via multimodal reactive oxygen species

Khan S. U., Eren G. O., Atac N., Onal A., Qureshi M. H., Cooper F. K., ...Daha Fazla

Chemical Engineering Journal, cilt.480, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 480
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1016/j.cej.2023.148140
  • Dergi Adı: Chemical Engineering Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aqualine, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, Food Science & Technology Abstracts, INSPEC, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Anahtar Kelimeler: Antibacterial, Escherichia coli, InP, Pseudomonas aeruginosa, Quantum dot, Reactive oxygen species, ROS, Type-II, ZnO, ZnS
  • Abdullah Gül Üniversitesi Adresli: Evet

Özet

The emergence of multidrug-resistant bacteria as a global health threat has necessitated the exploration of alternative treatments to combat bacterial infections. Among these, photocatalytic nanomaterials such as quantum dots (QDs) have shown great promise and type-I QDs have been investigated thus far. In this study, we introduce type-II InP/ZnO core/shell QDs that are ligand-exchanged with a short-chain inorganic sulfide ion (S2−) for antibacterial activity. Interestingly, InP/ZnO QDs simultaneously generate reactive oxygen species (ROS) including hydroxyl (•OH) and superoxide (O2•−) radicals, while only O2•− radicals can be released by the type-I sulfide-capped InP/ZnS QDs. The optimized nanostructure achieved effective inhibition of Pseudomonas aeruginosa and Escherichia coli bacteria growth to the level of 99.99% and 70.31% under low-intensity green light illumination of 5 mW.cm−2. Our findings highlight the importance of type-II QDs as a new avenue for developing effective antibacterial agents against drug-resistant pathogens.