Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells


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Avci C. B. , GÜNDÜZ C., Baran Y. , ŞAHİN F., Yilmaz S., Dogan Z. O. , ...More

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.137, no.1, pp.41-47, 2011 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 137 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1007/s00432-010-0857-0
  • Title of Journal : JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Page Numbers: pp.41-47

Abstract

CAPE (caffeic acid phenethyl ester) is one of the most valuable and investigated component of propolis which is composed by honeybees. In the current study, we aimed at examining apoptotic effects of CAPE on CCRF-CEM leukemic cells and at determining the roles of mitochondrial membrane potential (MMP) in cell death.