Concurrent inhibition of FLT3 and sphingosine kinase-1 triggers synergistic cytotoxicity in midostaurin resistant FLT3-ITD positive acute myeloid leukemia cells via blocking FLT3/STAT5A signaling to induce apoptosis

Tecik M., Adan A.

Journal of Chemotherapy, vol.38, no.2, pp.145-161, 2026 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 38 Issue: 2
• Publication Date: 2026
• Doi Number: 10.1080/1120009x.2025.2478340
• Journal Name: Journal of Chemotherapy
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, CAB Abstracts, MEDLINE, Veterinary Science Database
• Page Numbers: pp.145-161
• Keywords: drug resistance, FLT3-ITD AML, midostaurin, sphingosine kinase-1, STAT5A
• Abdullah Gül University Affiliated: Yes