Magnetic-particle based signal amplification method integrated with mobile-devices for low cost biosensing

Mzava O., Tas Z., Lafci V. C., Cakar M. A., Ozdur I., İÇÖZ K.

26th Anniversary World Congress on Biosensors (Biosensors), Gothenburg, Sweden, 25 - 27 May 2016, vol.27, pp.14-15 identifier

  • Publication Type: Conference Paper / Full Text
  • Volume: 27
  • Doi Number: 10.1016/j.protcy.2017.04.008
  • City: Gothenburg
  • Country: Sweden
  • Page Numbers: pp.14-15
  • Abdullah Gül University Affiliated: Yes

Abstract

We present a signal amplification method for biosensing applications using magnetic particles. In this method, mobile devices and simple spherical glass beads are used as a low-cost microscope to detect magnetic particles. Magnetic particles have two main functions; 1) conventionally capture, separate and transport target molecules 2) form magnetic dipoles under an applied external magnetic field to attract other magnetized particles. When magnetic particles accumulate and form a cluster, the corresponding pixel area in the image taken by the simple microscope is increased resulting in signal amplification.