Magnetic-particle based signal amplification method integrated with mobile-devices for low cost biosensing


Mzava O., Tas Z., Lafci V. C. , Cakar M. A. , Ozdur I., İÇÖZ K.

26th Anniversary World Congress on Biosensors (Biosensors), Gothenburg, İsveç, 25 - 27 Mayıs 2016, cilt.27, ss.14-15 identifier

  • Cilt numarası: 27
  • Doi Numarası: 10.1016/j.protcy.2017.04.008
  • Basıldığı Şehir: Gothenburg
  • Basıldığı Ülke: İsveç
  • Sayfa Sayıları: ss.14-15

Özet

We present a signal amplification method for biosensing applications using magnetic particles. In this method, mobile devices and simple spherical glass beads are used as a low-cost microscope to detect magnetic particles. Magnetic particles have two main functions; 1) conventionally capture, separate and transport target molecules 2) form magnetic dipoles under an applied external magnetic field to attract other magnetized particles. When magnetic particles accumulate and form a cluster, the corresponding pixel area in the image taken by the simple microscope is increased resulting in signal amplification.