Antiproliferative activity of (R)-4′-methylklavuzon on hepatocellular carcinoma cells and EpCAM+/CD133+ cancer stem cells via SIRT1 and Exportin-1 (CRM1) inhibition

Delman M., Avcı S. T., Akçok İ., Kanbur T., Erdal E., Çağır A.

European Journal of Medicinal Chemistry, cilt.180, ss.224-237, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 180
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.ejmech.2019.07.024
  • Dergi Adı: European Journal of Medicinal Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.224-237
  • Anahtar Kelimeler: Hepatocellular carcinoma, Cancer stem cell, SIRT1 inhibitor, CRM1 inhibitor, Topoisomerase I inhibitor, Klavuzon, IN-VITRO, NUCLEAR TRANSPORT, DRUG-RESISTANCE, GONIOTHALAMIN, P53, APOPTOSIS, ANTICANCER, ACTIVATION, MECHANISM, EXPRESSION
  • Abdullah Gül Üniversitesi Adresli: Evet