Antiproliferative activity of (R)-4′-methylklavuzon on hepatocellular carcinoma cells and EpCAM+/CD133+ cancer stem cells via SIRT1 and Exportin-1 (CRM1) inhibition

Delman M., Avcı S. T., Akçok İ., Kanbur T., Erdal E., Çağır A.

European Journal of Medicinal Chemistry, cilt.180, ss.224-237, 2019 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 180
• Basım Tarihi: 2019
• Doi Numarası: 10.1016/j.ejmech.2019.07.024
• Dergi Adı: European Journal of Medicinal Chemistry
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.224-237
• Anahtar Kelimeler: Hepatocellular carcinoma, Cancer stem cell, SIRT1 inhibitor, CRM1 inhibitor, Topoisomerase I inhibitor, Klavuzon, IN-VITRO, NUCLEAR TRANSPORT, DRUG-RESISTANCE, GONIOTHALAMIN, P53, APOPTOSIS, ANTICANCER, ACTIVATION, MECHANISM, EXPRESSION
• Abdullah Gül Üniversitesi Adresli: Evet