Active Subnetwork GA: A Two Stage Genetic Algorithm Approach to Active Subnetwork Search

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Atıf İçin Kopyala

ÖZIŞIK O., Bakir-Gungor B. , DİRİ B., Sezerman O. U.

CURRENT BIOINFORMATICS, cilt.12, ss.320-328, 2017 (SCI İndekslerine Giren Dergi)

• Cilt numarası: 12 Konu: 4
• Basım Tarihi: 2017
• Doi Numarası: 10.2174/1574893611666160527100444
• Dergi Adı: CURRENT BIOINFORMATICS
• Sayfa Sayısı: ss.320-328

Özet

Background: A group of interconnected genes in a protein-protein interaction network that contains most of the disease associated genes is called an active subnetwork. Active subnetwork search is an NP-hard problem. In the last decade, simulated annealing, greedy search, color coding, genetic algorithm, and mathematical programming based methods are proposed for this problem.