This course will emphasize the basics and mechanisms of eucaryotic gene regulation with a specific focus on newly emerging topics. This course will be using current literatüre together with a main textbook. Topics will include transcriptional regulation of eukaryotic gene expression including cis elements (promoters, enhancers and insulators) and trans elements (transcription factors), key modules of differential gene expression, chromatin remodeling, the posttranscriptional regulation of gene expression including RNA interference.